Cadherin-4/R-Cadherin Proteins and Enzymes

Cadherin-4, also known as R-Cadherin, is a 120-140 kDa type I transmembrane protein belonging to the Cadherin superfamily of calcium-dependent adhesion molecules. Cadherin-4 is expressed in epithelial cells, vascular smooth muscle cells, glial and neuronal cells, pancreatic beta-cells, thyroid follicular cells, and bone marrow Lin- hematopoietic stem cells. It interacts in cis to form homodimers as well as heterodimers with N-Cadherin which function as adhesion multimers in trans-configuration. ...