CDX2 Proteins and Enzymes

The caudal-type homeobox protein family of transcription factors are involved in early anteroposterior patterning by regulating members of the HOX gene family. CDX proteins contain a caudal-like activation domain and a DNA-binding homeodomain. CDX2 promotes intestinal patterning and development, while CDX4 regulates hematopoiesis and proliferation ...