DGAT1 Proteins and Enzymes

Diglyceride acyltransferase (DGAT) is a membrane-bound Sterol o-acyltransferase subfamily member. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. Specifically, it catalyzes the terminal step in triacylglycerol synthesis, using diacylglycerol (DAG) and fatty acyl CoA as substrates.

DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol ...