Dimethylarginine Dimethylaminohydrolase 1/DDAH1 Proteins and Enzymes

Dimethylarginine Dimethylaminohydrolase (DDAH) metabolizes asymmetric dimethyl arginine (ADMA) to L-citrulline and dimethylamine, and N^G-monomethyl arginine (MMA) to L-citrulline and monomethylamine. Two members of the DDAH family have been identified in humans. DDAH1 is widely expressed, especially in liver and kidney. DDAH2 predominates in vascular endothelium and expressed selectively in kidney. It is also expressed in immune tissues including spleen, thymus, peripheral leukocytes, lymph ...