FOXN4 Products

Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-aminoacid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helicesflanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as keyregulators in development and metabolism (Li et al., 2004 (PubMed 15363391)).(supplied by OMIM)