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Free Fatty Acid Receptor Inverse Agonists

Free Fatty Acid (FFA) receptors are a group of Gq/11 protein-coupled receptors that are currently classified into FFA1, FFA2, FFA3 and FFA4 subtypes. FFA receptors are concentrated in the pancreatic islet cells (particularly FFA1) and in the brain, with lower expression levels found in adipose tissue, peripheral blood mononuclear cells, neutrophils and monocytes.

FFAs 1, 2 and 3 genes are co-located on chromosome 19 and have closely related sequences, while FFA4 is located on chromosome 10 and ...

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FFA2 (GPR43) inverse agonist

Chemical Name: (S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoic acid
Purity: ≥98%
FFA2 (GPR43) inverse agonist
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