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1 result for "GABA-A R rho 1" in Products
GABA-A R rho 1 Products
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. GABA-A R rho 1 is a member of the rho subunit family and is highly expressed in the retina and in a lesser extent in brain, lung and thymus. GABA-A R rho 1 could play a role in retinal neurotransmission.
α5-selective GABAA inverse agonist
| Chemical Name: | 3-(1,1-Dimethylethyl)-7-(5-methyl-3-isoxazolyl)-2-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-pyrazolo[1,5-d][1,2,4]triazine |
| Purity: | ≥98% |
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