Hemopexin Proteins and Enzymes

Hemopexin (HPX) is a 60 kDa plasma glycoprotein with two four-bladed beta-propeller folds. This structural motif has been found in other proteins including collagenases and provides sites for protein-protein interactions. The liver is the major synthesizing organ. Expression in the central nervous system, in the retina, and in peripheral nerves has also been observed. Hemopexin belongs to the family of the acute-phase proteins whose synthesis is induced after an inflammatory event. Hemopexin ...