Hexosaminidase A/HEXA Small Molecules and Peptides

beta-Hexosaminidases are enzymes involved in the hydrolysis of terminal N-acetyl-D-hexosamine residues in GM2 gangliosides and globo-sphingolipids in lysosomes. The enzymes are composed of two alpha and/or beta subunits, which are coded by HEXA and HEXB genes, respectively. Different associations of the alpha and beta subunits gives rise to beta-hexosaminidase isoforms A, B and S (Hex A, B and S), which have the composition of alpha/beta, beta/beta and alpha/alpha, respectively. Our recombinant ...