Humanin Proteins and Enzymes

A gene, Humanin, encodes a short polypeptide and abolishes death of neuronal cells caused by multiple different types of familial Alzheimer's disease genes and by Abeta amyloid, without effect on death by Q79 or superoxide dismutase-1 mutants. This polypeptide serves as a molecular clue for the development of new therapeutics for Alzheimer's disease targeting neuroprotection.