HypoxiTRAK(TM) Fluorescent Probes and Dyes

Hypoxia is a physiological state characterized by low oxygen levels in tissues and organs. Decreased oxygen levels can affect biological and cellular processes such as cell growth, proliferation, differentiation, metabolism, and angiogenesis (1). Therefore, hypoxia is also a common feature of many malignancies such as various cancers and inflammatory diseases (1,2). Hypoxia is regulated by hypoxia-inducible factors (HIFs). Under normoxia, HIFs are targeted for ubiquitin degradation initiated by ...