1 result for "Integrin alpha V beta 3" in Products

Integrin alpha V beta 3 Products

Integrin alpha V beta 3 (aVb3) is a heterodimeric adhesion protein that is highly expressed on endothelial cells and osteoclasts. Active cell surface aVb3 binds to the extracellular matrix proteins Vitronectin, Fibronectin, Fibrinogen and Thrombospondin. It is essential for the maturation of osteoclasts and their bone resorption activity. Loss of a...

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Reactivity: Human
Source: CHO
Accession #: NP_002201 (Integrin alpha V) & AAA52589 (Integrin beta 3)
Applications: Binding Activity
R&D Systems Recombinant Proteins and Enzymes
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