175 results for "Integrin alpha V beta 3" in Products
Integrin alpha V beta 3 Products
Integrin alpha V beta 3 (aVb3) is a heterodimeric adhesion protein that is highly expressed on endothelial cells and osteoclasts. Active cell surface aVb3 binds to the extracellular matrix proteins Vitronectin, Fibronectin, Fibrinogen and Thrombospondin. It is essential for the maturation of osteoclasts and their bone resorption activity. Loss of aVb3 function during osteoclastogenesis causes osteoporosis. In addition, aVb3 enhances VEGF R2 mediated angiogenesis, IGF-1 mediated tumor cell invasiveness, and cell entry by several viruses.
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | NP_002201 (Integrin alpha V) & AAA52589 (Integrin beta 3) |
| Applications: | Binding Activity |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | B/N, Flow, IP, CyTOF-ready |
| Reactivity: | Mouse |
| Source: | CHO |
| Accession #: | P43406 (Integrin alpha V) & O54890 (Integrin beta 3) |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | Flow |
| Reactivity: | Cynomolgus Monkey |
| Source: | CHO |
| Accession #: | XP_005573729.1 (Integrin alpha V) & XP_005584667.1 (Integrin beta 3) |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | IHC, Flow, IP, CyTOF-ready |
Fc Chimera
| Reactivity: | Human |
| Source: | HEK293 |
| Applications: | Bioactivity |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2549B |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | IHC, Flow, IP, CyTOF-ready |
αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor
| Purity: | ≥95% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | Flow |
| Reactivity: | Human, Rat, Chicken |
| Details: | Mouse IgG1 Monoclonal Clone #BV3 |
| Applications: | IHC, ELISA, Flow, ICC/IF, IP |
![Flow Cytometry: Integrin alpha V beta 3 Antibody (BV3) [NBP3-11213]](https://resources.rndsystems.com/images/products/Integrin-alpha-V-beta-3-Antibody-BV3-Flow-Cytometry-NBP3-11213-img0001.jpg "Flow Cytometry: Integrin alpha V beta 3 Antibody (BV3) [NBP3-11213]")
Potent integrin inhibitor (αvβ3/αvβ6); also improves stem cell attachment in 3D cell culture scaffolds
| Purity: | ≥95% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #27.1 (VNR-1) |
| Applications: | IHC, ICC/IF, IP, IHC-P (-) |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2549B |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2549B |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2549B |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2549B |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2549B |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2549B |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2549B |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #23C6 |
| Applications: | Flow |