MAGP-2/MFAP5 Proteins and Enzymes

MAGP-2 (Microfibril-associated glycoprotein 2), also called MFAP5 (microfibril associated protein 5) is a secreted, cell-associated 25 kDa mammalian member of the MFAP family of proteins. Human MAGP-2 cDNA encodes 173 amino acids (aa) including a 21 aa signal sequence, an RDG motif (aa 30-32; absent in MAGP-1) and a central cysteine-rich binding domain (aa 84-140). One potential splice variant shows a 10 aa deletion between aa 73-82 that includes the only potential glycosylation site. Mature ...