MKK4 Proteins and Enzymes

MKK4, also known as MEK4, JNKK1, SEK1, MAP2K4, is an intracellular protein kinase that functions in the JNK (Jun N-terminal kinase) signal transduction pathway. In response to activation by one of several MAPKKKs, MKK4 (and MKK7) phosphorylates and activates the JNKs that regulate neural development, apoptosis, inflammation, and cellular responses ...