NAGS Proteins and Enzymes

NAGS (N-acetylglutamate synthase) is involved in the regulation of ureagenesis since it produces NAG, which is a cofactor of CPSI. NAGS is known to have interactions with TMEM39B, ASS1, ADSSL1, SNRPD3, and RPS16. NAGS has been studied in relation to several diseases and disorders including hepatitis, Urea Cycle Disorder, propionic academia, hyperargininemia, Celiac disease and metabolic disorders.