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1 result for "Non-selective Endothelin Receptor Antagonists" in Products
Non-selective Endothelin Receptor Antagonists
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells whe...
High affinity dual ETA and ETB receptor antagonist;orally bioavailable
| Alternate Names: | Ro 47-0203 |
| Chemical Name: | 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide |
| Purity: | ≥98% |
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