Norrin Proteins and Enzymes

Norrin (also called Norrie Disease Protein or NDP) is a secreted regulatory protein, mutations in which cause Norrie disease (X-linked retinal dysplasia). Norrin consists of disulfide-linked homodimers that oligomerize further via disulfide bridges to form higher order oligomers containing up to ten units of 12 kDa each. Molecular modeling studies ...