Olfactomedin-1/Noelin-1 Proteins and Enzymes

Olfactomedin-1, also known as Noelin-1 (neuronal olfactomedin-related endoplasmic reticulum-localized-1), or pancortin, is a 75 kDa secreted extracellular matrix glycoprotein expressed in the brain. Alternate promoter usage and splicing creates four forms of Noelin (Noelin 1-4) that are combinations of a common central region with alternate N- and C-termini. Olfactomedin-1/Noelin-1 is the longest of the four isoforms, encoding a 16 amino acid (aa) signal sequence and a 469 aa mature protein ...