Organoid Compounds Small Molecules and Peptides

Organoids are cultured from adult stem cells or from cells differentiated from pluripotent stem cells, self-organized through cell sorting (see image below). Different types of cells arrange themselves based on the distinct expression profiles of cellular adhesion molecules and spatially restricted lineage commitment. Spatially constraining cells in tissue or artificial conditions promotes further differentiation of stem cells and is crucial in the generation of organoids. In the laboratory, ...