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PI 3-Kinase Activators

PI 3-Kinases (phosphoinositide 3-kinases, PI 3-Ks) are a family of lipid kinases capable of phosphorylating the 3'OH of the inositol ring of phosphoinositides. They are responsible for coordinating a diverse range of cell functions including proliferation, cell survival, degranulation, vesicular trafficking and cell migration.

The PI 3-kinases are grouped into three distinct classes. Class I PI 3-kinases are heteromeric consisting of a regulatory subunit and a 110 kDa catalytic subunit (3 ...

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Molecular glue increasing the binding affinity of PI3Kα catalytic subunit p110α to canonical small guanosine triphosphatase RAS proteins

Chemical Name: 3-Fluoro-4-[[7-[2-(2-methoxyethoxy)phenyl]thieno[2,3-d]pyridazin-4-yl]amino]benzeneacetamide
Purity: ≥98%
Molecular glue increasing the binding affinity of PI3Kα catalytic subunit p110α to canonical small guanosine triphosphatase RAS proteins
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