PlGF-4 Proteins and Enzymes

PlGF (placenta growth factor) is secreted primarily by villous trophoblasts and decidual cells, with circulating levels increasing during pregnancy but attenuated in preeclampsia. Alternative splicing generates multiple human PlGF isoforms (PlGF‑1, ‑2, ‑3, and -4). PlGF signals through VEGF R1/Flt‑1 and Neuropilins, whil...