PP2C alpha/PPM1A Proteins and Enzymes

Protein phosphatase 2C alpha, also called PP2C alpha, Protein Phosphatase, Magnesium-dependent type 1A, and PPM1A, dephosphorylates proteins with some preference for phospho-threonine over phospho-serine residues. It is insensitive to the PP1 and PP2a inhibitors such as okadaic acid, but has an absolute requirement for either magnesium or manganese...