3 results for "PPAR gamma Receptor Antagonists Small Molecules and Peptides" in Products
PPAR gamma Receptor Antagonists Small Molecules and Peptides
Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression. PPARγ is located primarily in the adipose tissue, lymphoid tissue, colon, liver and heart and is thought to regulate adipocyte differentiation and glucose homeostasis. PPARγ has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. The human gene encoding PPARγ has been localized to chromosome 3 (3p25).
Selective covalent PPARγ antagonist
| Chemical Name: | 2-Chloro-5-nitro-N-phenylbenzamide |
| Purity: | ≥98% |
Highly potent and selective covalent PPARγ antagonist
| Chemical Name: | 2-Chloro-5-nitro-N-4-pyridinylbenzamide |
| Purity: | ≥98% |
Dual site PPARγ inhibitor
| Chemical Name: | 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide |
| Purity: | ≥98% |
