T 0070907

  ( 1 citations )    
Product Datasheet
Catalog Number:2301
Chemical Name:2-Chloro-5-nitro-N-4-pyridinylbenzamide
Product Details
Citations (1)
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Reviews
Biological Activity
Potent and selective irreversible PPARγ antagonist (IC50 = 1 nM). Displays > 800-fold selectivity for PPARγ over PPARα and PPARδ. Blocks transcriptional activity of PPARγ in vitro and inhibits rosiglitazone-induced adipogenesis.
Technical Data
  • M.Wt:
    277.67
  • Formula:
    C12H8N3O3Cl
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    313516-66-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for T 0070907 include:

1 Citations: Showing 1 - 1

  1. The human tissue-biomaterial interface: a role for PPARγ-dependent glucocorticoid receptor activation in regulating the CD163+ M2 macrophage phenotype.
    Authors: Bullers Et al.
    Tissue Eng Part A  2014;20:2390

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