Potent and selective PPARγ
= 1 nM). Displays > 800-fold selectivity for PPARγ
. Blocks transcriptional activity of PPARγ in vitro
and inhibits rosiglitazone-induced adipogenesis.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
T0070907, a selective ligand for peroxisome proliferator-activated receptor γ, functions as an antagonist of biochemical and cellular activities.
Lee et al.
A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes.
Rockwell and Kaminski
Peroxisome proliferator-activated receptor γ inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells.
Schaefer et al.
Cancer Res., 2005;65:2251
The citations listed below are publications that use Tocris products. Selected citations for T 0070907 include:
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