Chemical Name: 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
Biological ActivityDual site PPARγ inhibitor. Acts at orthosteric and allosteric sites in the ligand binding domain. Inhibits binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonists GW 9662 (Cat. No. 1508) and T 0070907 (Cat. No. 2301).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Modification of the othosteric PPARγ covalent antagonist scaffold yields an improved dual-site allosteric inhibitor.
Brust et al.
ACS Chem.Biol., 2017;12:969
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for SR 16832
There are currently no reviews for this product. Be the first to review SR 16832 and earn rewards!
Have you used SR 16832?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image