1 result for "Prokineticin R2/PROKR2 Small Molecules and Peptides" in Products

Prokineticin R2/PROKR2 Small Molecules and Peptides

Corticotropin Releasing Factor Receptor 2 (CRHR2) expression has been reported in various regions of the brain, as well as in placenta, umbilical vein, heart, epididymis, gastrointestinal tract, adrenal, and skeletal muscle. It shows high-affinity CRF binding and also binds to urocortin I, II and III. The activity of this receptor is mediated by G ...

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Potent prokineticin (PK) 1 and 2 receptor antagonist; antitumor; BBB penetrant

Alternate Names: PROK2 Antagonist,Bv8 Antagonist,PK2 Antagonist,Prokineticin 2 Antagonist
Chemical Name: (3R)-N-[(9-Chloro-3,4-dihydro-2H-1,5-benzodioxepin-7-yl)methyl]-1-[(4-fluoro-3-methoxyphenyl)methyl]-N-(2-methylpropyl)-3-pyrrolidinecarboxamide hydrochloride
Purity: ≥98%
Potent prokineticin (PK) 1 and 2 receptor antagonist; antitumor; BBB penetrant
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