Tyrosine Hydroxylase Proteins and Enzymes

Tyrosine Hydroxylase (TH) is the rate limiting enzyme involved in the biosynthesis of catecholamines. It catalyzes the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA), which is the precursor for dopamine. Dopamine, in turn, can be converted into norepinephrine and epinephrine. TH is expressed in dopaminergic and nor...