Urotensin-II R CDNA Clones

Urotensin-II Receptor belongs to the G protein-coupled receptor 1 family. Urotensin-II R is a high affinity receptor for Urotensin-2 and Urotensin-2B. The activity of Urotensin-II R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Urotensin-II R has been correlated with human cortico-adrenal carcinoma proliferation.