VIGR/GPR126 Proteins and Enzymes

VIGR encodes a G protein-coupled receptor that is expressed in placenta and to a lower extent in pancreas and liver. VIGR represents a novel GPCR of the adhesion family, which is unique in its long extra-cellular domain comprising CUB and PTX-like modules. It is induced by LPS and thrombin in a subset of ECs, suggesting an important function in cel...