Members of the MAPK family, the c-Jun N-terminal kinases (JNKs) are activated by environmental stresses and inflammatory cytokines. Ten JNK isoforms are created by alternative splicing of mRNA transcripts derived from three genes: JNK1, JNK2, and JNK3. All JNKs are activated by dual phosphorylation; at T183/Y185 for JNK1 and 2, and T221/Y223 for JNK3. Activated JNKs translocate to the nucleus where they regulate the activity of several transcription factors; including the c-Jun component of AP-1 and ATF-2.
Human/Mouse/Rat Phospho-JNK Pan Specific DuoSet IC ELISA
R&D Systems | Catalog # DYC1387-2
Discontinued Product
DYC1387-2 has been discontinued.
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Product Specifications
Detection Method
Colorimetric ELISA - 450nm (TMB)
Conjugate
Unconjugated
Specificity
Label
HRP
Preparation and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: JNK
Long Name
C-Jun N-terminal Kinase
Alternate Names
c-Jun N-terminal kinase 1, EC 2.7.11, EC 2.7.11.24, JNK1 alpha protein kinase, JNK1 beta protein kinase, JNK1JNK1A2, JNK-46, JUN N-terminal kinase, MAP kinase 8, MAPK 8, mitogen-activated protein kinase 8, mitogen-activated protein kinase 8 isoform JNK1 alpha1, mitogen-activated protein kinase 8 isoform JNK1 beta2, PRKM8JNK, protein kinase JNK1, SAPK1JNK21B1/2, Stress-activated protein kinase 1, Stress-activated protein kinase JNK1
Additional JNK Products
Product Documents for Human/Mouse/Rat Phospho-JNK Pan Specific DuoSet IC ELISA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human/Mouse/Rat Phospho-JNK Pan Specific DuoSet IC ELISA
For research use only
Citations for Human/Mouse/Rat Phospho-JNK Pan Specific DuoSet IC ELISA
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