1-EBIO

Tocris Bioscience | Catalog # 1041

Epithelial KCa channel activator
Tocris Bioscience
Discontinued Product
1041 has been discontinued. View all Ca2+-Activated Potassium Channel Activators products.

Key Product Details

Description

Epithelial KCa channel activator
View all Ca2+-Activated Potassium Channel Activators »

Product Description

1-EBIO is an activator of epithelial KCa channels, stimulates a large and sustained trans-epithelial Cl- secretory response across T84 monolayers. Induces hyperpolarization to the same magnitude as ACh in aortic value endothelial cells. Promotes embryonic stem cell (ESC) differentiation into cardiomyocytes.

Product Specifications for 1-EBIO

Molecular Weight

162.19

Formula

C9H10N2O

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

1-Ethyl-2-benzimidazolinone

CAS Number

10045-45-1

PubChem ID

82320

InChI Key

CXUCKELNYMZTRT-UHFFFAOYSA-N

SMILES

CCN1C(=O)NC2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 16.22 100
Ethanol 16.22 100

Preparing Stock Solutions for 1-EBIO

The following data is based on the product molecular weight 162.19.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.17 mL 30.83 mL 61.66 mL
5 mM 1.23 mL 6.17 mL 12.33 mL
10 mM 0.62 mL 3.08 mL 6.17 mL
50 mM 0.12 mL 0.62 mL 1.23 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 86 publications citing the usage of this product.

Product Documents for 1-EBIO

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 1-EBIO

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for 1-EBIO (1)

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  • Study on BK channel activity
    Name: Eleanor Baxter
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 10/23/2018
    It activates Ca2+ activated K+ channels on epithelium. Our University lab uses it to study Big Conductance Channel channel opening.
    1-EBIO 1041

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