10 results for "Ca2+-Activated Potassium Channel Activators" in 产品

Ca2+-Activated Potassium Channel Activators

There are 8 members of the KCa channel family, all of which are homo or heterotetramers of α-subunits, with either 6 or 7 transmembrane domains. Some family members also have associated regulatory subunits. KCa1.1 (BK), KCa2.x (SK) and KCa3.1 (IK) ion channels open in response to intracellular Ca2+ levels. Other KCa family members, KCa4.1, KCa4.2 (now known as KNa1.1 and KNa1.2) and KCa5.1 are grouped with KCa1.1 (BK) based on their structural similarities, however relatively little is ...

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KCa1.1 (BK) channel activator

Chemical Name: 1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one
Purity: ≥98%
KCa1.1 (BK) channel activator
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KCa1.1 (BK) channel activator

Chemical Name: N'-[3,5-Bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl-phenyl]thiourea
Purity: ≥98%
KCa1.1 (BK) channel activator
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Activates Cl- conductance and hKCa3.1 channels

Chemical Name: 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one
Purity: ≥99%
Activates Cl- conductance and hKCa3.1 channels
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Potent KCa1.1 (BK) channel opener

Chemical Name: 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one
Purity: ≥98%
Potent KCa1.1 (BK) channel opener
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KCa3.1 (IK) and KCa2 (SK) channel activator

Chemical Name: Naphtho[1,2-d]thiazol-2-ylamine
Purity: ≥99%
KCa3.1 (IK) and KCa2 (SK) channel activator
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Positive modulator of KCa2 (SK) and KCa3.1 (IK) channels

Chemical Name: 6,7-Dichloro-1H-indole-2,3-dione 3-oxime
Purity: ≥98%
Positive modulator of KCa2 (SK) and KCa3.1 (IK) channels
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Selective KCa2.1 (SK) channel activator

Chemical Name: 4-[[[[(2-Methoxyphenyl)amino]carbonyl]oxy]methyl]-piperidinecarboxylic acid-1,1-dimethylethyl ester
Purity: ≥99%
Selective KCa2.1 (SK) channel activator
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KCa1.1 (BK) channel activator

Chemical Name: 5-[(4-Bromophenyl)methyl]-2-thiazolamine
Purity: ≥99%
KCa1.1 (BK) channel activator
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KCa2.2 and KCa2.3 (SK) channel activator

Chemical Name: N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine
Purity: ≥99%
KCa2.2 and KCa2.3 (SK) channel activator
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KCa1.1 (BK) channel activator

Chemical Name: Sodium 1-Amino-9,10-dioxo-4-((5,6,7,8-tetrahydronaphthalen-2-yl)amino)-9,10-dihydroanthracene-2-sulfonate
Purity: ≥98%
KCa1.1 (BK) channel activator
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