7-Hydroxy-DPAT hydrobromide
Tocris Bioscience | Catalog # 0706
Key Product Details
Description
Product Description
7-Hydroxy-DPAT hydrobromide is a D3 dopamine receptor agonist (Ki values are ~ 1, 10, 650 and ~ 5000 nM for D3, D2, D4 and D1 receptors respectively).
8-Hydroxy Isomer also available.
Product Specifications for 7-Hydroxy-DPAT hydrobromide
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 32.83 | 100 |
Preparing Stock Solutions for 7-Hydroxy-DPAT hydrobromide
The following data is based on the product molecular weight 328.28.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.05 mL | 15.23 mL | 30.46 mL |
| 5 mM | 0.61 mL | 3.05 mL | 6.09 mL |
| 10 mM | 0.30 mL | 1.52 mL | 3.05 mL |
| 50 mM | 0.06 mL | 0.30 mL | 0.61 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Seeman and Van Tol DA receptor pharmacology. TiPS 1994 PMID: 7940991
- Levesque Aminotetralin drugs and D3 receptor fuctions. Biochem.Pharmacol. 1996 PMID: 8759022
- Levesque Identification, characterization, and localization of the DA D3 receptor in rat brain using [3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc.Natl.Acad.Sci.U.S.A. 1992 PMID: 1518841
- Daly and Waddington Behavioural effects of the D3 DA receptor agonist 7-OH-DPAT in relation to other D2-like agonists. Neuropharmacology 1993 PMID: 8321432
Product Documents for 7-Hydroxy-DPAT hydrobromide
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for 7-Hydroxy-DPAT hydrobromide
For research use only
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