8-Hydroxy-DPAT hydrobromide

Tocris Bioscience | Catalog # 0529

Selective 5-HT1A agonist; also has moderate affinity for 5-HT7
Tocris Bioscience
Discontinued Product
0529 has been discontinued. View all 5-HT1 Receptor Agonists products.

Key Product Details

Description

Selective 5-HT1A agonist; also has moderate affinity for 5-HT7

Alternative Names

8-OH-DPAT hydrobromide
View all 5-HT1 Receptor Agonists »

Product Description

The standard selective 5-HT1A agonist. Also has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells). Reduces hippocampal 5-HT levels following systemic administration in rats in vivo.

R-enantiomer and 7-Hydroxy Isomer also available..

Product Specifications for 8-Hydroxy-DPAT hydrobromide

Molecular Weight

328.29

Formula

C16H25NO.HBr

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

(±)-8-Hydroxy-2-dipropylaminotetralin hydrobromide

CAS Number

76135-31-4

PubChem ID

6917794

InChI Key

BATPBOZTBNNDLN-UHFFFAOYSA-N

SMILES

Br.CCCN(CCC)C1CCC2=CC=CC(O)=C2C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 3.28 10 with gentle warming
DMSO 16.41 50

Preparing Stock Solutions for 8-Hydroxy-DPAT hydrobromide

The following data is based on the product molecular weight 328.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 6.09 mL 30.46 mL 60.92 mL
2.5 mM 1.22 mL 6.09 mL 12.18 mL
5 mM 0.61 mL 3.05 mL 6.09 mL
25 mM 0.12 mL 0.61 mL 1.22 mL

Calculators

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Product Documents for 8-Hydroxy-DPAT hydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 8-Hydroxy-DPAT hydrobromide

For research use only

Citations for 8-Hydroxy-DPAT hydrobromide

Customer Reviews for 8-Hydroxy-DPAT hydrobromide (1)

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  • 5-HT has a potential for relaxant
    Name: Anonymous
    Species: Rat
    Assay Type: In Vivo
    Verified Customer | Posted 02/18/2020
    5-HT1A/7 receptor (8-OHDPAT) (0.1 lmol/L)
    8-Hydroxy-DPAT hydrobromide 0529

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