BOP-JF646

Tocris Bioscience | Catalog # 6997

Red fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 646; fluorogenic; photostable
Tocris Bioscience
Discontinued Product
6997 has been discontinued. View all Fluorescent Integrins Probes products.

Key Product Details

Description

Red fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 646; fluorogenic; photostable

Wavelength

Excitation = 655 nm, Emission = 672 nm
View all Fluorescent Integrins Probes »

Product Description

BOP-JF646 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP (Cat. No. 6047) conjugated to Janelia Fluor® 646 (Cat. No. 6148). Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 655 nm; emission maximum = 672 nm.

Scientific Data Images for BOP-JF646

Application of BOP-JF549

Application of BOP-JF549 in Immortalized Human Keratinocyte Cells.

Immortalized human keratinocytes expressing a GFP-tagged alpha 4 integrin were incubated with 10 μm BOP-Janelia Fluor® 568. Cells were incubated at 37°C and imaged using Nikon A1R confocal microscope. Scale bar = 10 μm.Image kindly provided by Willow Hight-Warburton; Kings College London.

Optical Data

BOP-JF646 Dye Spectra
Emission Color Red
Brightness
λabs 655 nm
λem 672 nm
Closest Laser line 647 nm
Application Flow Cytometry, Confocal Microscopy, Super Resolution Microscopy (SRM)

Spectra Viewer

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Product Specifications for BOP-JF646

Molecular Weight

1090.30

Formula

C57H59N9O10SSi

Storage

Store at -20°C

Purity

≥90% (HPLC)

Chemical Name

2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-5-(((1-((3R,5S)-5-(((S)-1-carboxy-2-(4-((pyrrolidine-1-carbonyl)oxy)phenyl)ethyl)carbamoyl)-1-(phenylsulfonyl)pyrrolidin-3-yl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)benzoate

InChI Key

NHBQNNGTILNQPL-HXFFEZBUSA-N

SMILES

OC([C@@H](NC([C@@H]1C[C@@H](N2C=C(CNC(C3=CC=C(C([O-])=O)C(C(C4=CC=C(N5CCC5)C=C4[Si]6(C)C)=C(C=C/7)C6=CC7=[N+]8CCC\8)=C3)=O)N=N2)CN1S(=O)(C9=CC=CC=C9)=O)=O)CC%10=CC=C(C=C%10)OC(N%11CCCC%11)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

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Product Documents for BOP-JF646

Certificate of Analysis

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Product Specific Notices for BOP-JF646

For research use only

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