Human Caspr1 ELISA Kit (Colorimetric)

Novus Biologicals | Catalog # NBP2-75813

Novus Biologicals
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Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma and other biological fluids (100 uL)

Sensitivity

0.10 ng/mL

Assay Range

0.16 - 10 ng/mL
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Product Specifications

Assay Type

Sandwich-ELISA

Kit Type

ELISA Kit (Colorimetric)

Species

Human

Specificity

This kit recognizes Human CNTNAP1 in samples. No significant cross-reactivity or interference between Human CNTNAP1 and analogues was observed.

精度

Intra-Assay Precision (Precision within an assay) CV% 5.44%

Inter-Assay Precision (Precision between assays) CV% 5.52%

Recovery for Human Caspr1 ELISA Kit (Colorimetric)

Recovery

85-106%

Linearity

Human Caspr1 ELISA Kit (Colorimetric)

Scientific Data Images for Human Caspr1 ELISA Kit (Colorimetric)

Human Caspr1 ELISA Kit (Colorimetric)

ELISA: Human Caspr1 ELISA Kit (Colorimetric) [NBP2-75813] -

ELISA: Human Caspr1 ELISA Kit (Colorimetric) [NBP2-75813] - Standard Curve Reference

Kit Contents for Human Caspr1 ELISA Kit (Colorimetric)

  • Biotinylated Detection Ab Diluent
  • Concentrated Biotinylated Detection Ab (100x)
  • Concentrated HRP Conjugate (100x)
  • Concentrated Wash Buffer (25x)
  • HRP Conjugate Diluent
  • Micro ELISA Plate (Dismountable)
  • Plate Sealer
  • Product Manual
  • Reference Standard
  • Sample Diluent
  • Stop Solution
  • Substrate Reagent

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Caspr1

Contactin-associated protein 1 (Caspr1), also known as Neurexin-4, Paranodin, and NCP1, is an approximately 190 kDa transmembrane protein that is concentrated at paranodal junctions of axons during myelination. It is required for junction formation and ion channel localization and plays an important role in the propagation of saltatory nerve conduction. Caspr1 interacts with Contactins and Nogo-A at the paranodal junction and inhibits the binding of Contactin to glial cell Neurofascin. Caspr1 is proteolytically cleaved by Reelin, and this action is inhibited by the cellular prion protein (PrP). The ECD contains one Factor 5/8-like domain, four Laminin-G-like domains, two EGF-like domains, and one Fibrinogen-like domain.

Long Name

Contactin Associated Protein-like 1

Alternate Names

CNTNAP, CNTNAP1, p190

Gene Symbol

CNTNAP1

Additional Caspr1 Products

Product Documents for Human Caspr1 ELISA Kit (Colorimetric)

Certificate of Analysis

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Product Specific Notices for Human Caspr1 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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