CCT 031374 hydrobromide

Tocris Bioscience | Catalog # 4675

Inhibits TCF-dependent transcription; lowers β-catenin levels
Tocris Bioscience
Discontinued Product
4675 has been discontinued. View all beta-Catenin Inhibitors products.

Key Product Details

Description

Inhibits TCF-dependent transcription; lowers β-catenin levels
View all beta-Catenin Inhibitors »

Product Description

CCT 031374 hydrobromide is an inhibitor of TCF-dependent transcription. Blocks BIO-induced β-catenin stabilization; reduces nuclear and cytosolic β-catenin levels in mouse L-cells. Inhibits growth and reduces TCF-dependent transcription in SW480 colon carcinoma cells.

Product Specifications for CCT 031374 hydrobromide

Molecular Weight

434.33

Formula

C23H19N3O.HBr

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

1-[1,1'-Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanone hydrobromide

CAS Number

1219184-91-4

PubChem ID

18554738

InChI Key

MPILENOYNNNGKO-UHFFFAOYSA-N

SMILES

O=C(C4=CC=C(C5=CC=CC=C5)C=C4)CN1C3=C(C=CC=C3)N2C1=NCC2.Br

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 21.72 50

Preparing Stock Solutions for CCT 031374 hydrobromide

The following data is based on the product molecular weight 434.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.60 mL 23.02 mL 46.05 mL
2.5 mM 0.92 mL 4.60 mL 9.21 mL
5 mM 0.46 mL 2.30 mL 4.60 mL
25 mM 0.09 mL 0.46 mL 0.92 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for CCT 031374 hydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CCT 031374 hydrobromide

For research use only

Citations for CCT 031374 hydrobromide

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