CMBL Antibody (2B11) - BSA Free

Novus Biologicals | Catalog # NBP2-22618

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2B11

Format

BSA Free
View all CMBL Primary Antibodies »

Product Specifications

Immunogen

Recombinant human CMBL (1-245aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for CMBL Antibody (2B11) - BSA Free

Western Blot: CMBL Antibody (2B11)BSA Free [NBP2-22618]

Western Blot: CMBL Antibody (2B11)BSA Free [NBP2-22618]

Western Blot: CMBL Antibody (2B11) [NBP2-22618] - The extracts of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CMBL antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Applications for CMBL Antibody (2B11) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:500-1:5000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CMBL

CMBL(carboxymethylenebutenolidase homolog) is a 245 amino acid cytosolic protein and cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL is the human homolog of Pseudomonas dienelactone hydrolase, a protein that participates in the bacterial halocatechol degradation pathway. That is ubiquitously expressed with high expression in liver, colon, kidney and small intestine, where it acts as a bioactivating enzyme for a prodrug type angiotensin II type 1 receptor antagonist known as olmesartan medoxomil. CMBL is inhibited by p-chloromercuribenzoate (PCMB).

Alternate Names

carboxymethylenebutenolidase homolog, carboxymethylenebutenolidase homolog (Pseudomonas), carboxymethylenebutenolidase-like (Pseudomonas), EC 3.1, FLJ23617

Gene Symbol

CMBL

UniProt

NP_620164 (Human)

Additional CMBL Products

Product Documents for CMBL Antibody (2B11) - BSA Free

Certificate of Analysis

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Product Specific Notices for CMBL Antibody (2B11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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