Collagen V Antibody [Biotin]

Novus Biologicals | Catalog # NBP1-26552

Novus Biologicals

Key Product Details

Species Reactivity

Human, Bovine, Equine

Applications

ELISA

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all Collagen V Primary Antibodies »

Product Specifications

Immunogen

Goats were hyperimmunized with human type V collagen.

Specificity

Reacts with conformational determinants on human type V collagen as demonstrated by ELISA. May react with type V collagen from other species. Exhibits <10% cross reactivity with collagen type I, II, III, IV and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Collagen V Antibody [Biotin]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Collagen V

Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.

Alternate Names

alpha 1 type V collagen, Collagen 5, collagen alpha-1(V) chain, collagen, type V, alpha 1, Collagen-5, EC 2.7.7.6, EC 6.1.1

Gene Symbol

COL5A1

Additional Collagen V Products

Product Documents for Collagen V Antibody [Biotin]

Certificate of Analysis

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Product Specific Notices for Collagen V Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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