Complement C5 Antibody (557) - Azide Free

Novus Biologicals | Catalog # NB110-12179

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Western Blot, ELISA, Immunoassay, Block/Neutralize, Functional

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 557

Format

Azide Free
View all Complement C5 Primary Antibodies »

Product Specifications

Immunogen

BALB/c mice were immunized with human C5

Specificity

This reacts with an epitope on C5 and C5a.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Description

Novus Biologicals Mouse Complement C5 Antibody (557) - Azide Free (NB110-12179) is a monoclonal antibody validated for use in WB and ELISA. Anti-Complement C5 Antibody: Cited in 7 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.

Applications for Complement C5 Antibody (557) - Azide Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:1000
Application Notes
IA: Use at an assay dependent dilution. Inhib: Use at an assay dependent dilution. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 0.1% BSA

Format

Azide Free

Preservative

No Preservative

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Complement C5

C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5. C5a induces smooth muscle contraction, increases vascular permeability, and causes degranulation of mast cells and basophils, and release of lysosomal enzymes. In addition C5a stimulates the directed migration of neutrophils, eosinophils, basophils and monocytes. Recent studies indicate the modulation of the acute-phase response in liver and an overall immune response by inducing synthesis of cytokines such as TNF-a, IL-1a, IL-6 and IL-8.

Alternate Names

anaphylatoxin C5a analog, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5, complement C5, complement component 5, CPAMD4MGC142298, FLJ17816, FLJ17822

Entrez Gene IDs

727 (Human)

Gene Symbol

C5

UniProt

P01031

Additional Complement C5 Products

Product Documents for Complement C5 Antibody (557) - Azide Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Complement C5 Antibody (557) - Azide Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Complement C5 Antibody (557) - Azide Free

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FAQs for Complement C5 Antibody (557) - Azide Free

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  • Q: I am interested in purchasing the following antibody: catalog # NB110-12179 Complement C5 Antibody in which epitope its been raised against? What volume do you get out of 0.05mg? Also, what is its cost?

    A: NB110-12179 is not epitope mapped but it is known that it reacts with an epitope on C5 and C5a. The concentration is 0.1 mg/mL which is a volume of 500 uL. Regarding the price of this product, please use our website to select your country, which will allow you to view the country specific pricing, availability and technical support information.

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