Human Complement Factor B ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

精度

Intra-Assay Precision (Precision within an assay) CV% 4.80% (example only; lot dependent)

Inter-Assay Precision (Precision between assays) CV% 8.10% (example only; lot dependent)

Recovery for Human Complement Factor B ELISA Kit (Colorimetric)

Scientific Data Images for Human Complement Factor B ELISA Kit (Colorimetric)

Preparation and Storage

Background: Complement Factor B

Complement factor B is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Additional Complement Factor B Products

• All Products for Complement Factor B
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• Complement Factor B Proteins and Enzymes

Product Documents for Human Complement Factor B ELISA Kit (Colorimetric)