Crotonic Acid

Key Product Details

Product Description

Crotonic Acid is an induces histone modifications in chemically induced pluripotent stem cells (CiPSCs). Activates gene expression, facilitates telomere maintenance and increases telomere length, and enhances reprogramming of MEFs to iPSCs using a small molecule cocktail including valproic acid (Cat. No. 2815), CHIR 99021 (Cat. No. 4423), tranylcypromine (Cat. No. 3852), forskolin (Cat. No. 1099), AM 580 (Cat. No. 0760), EPZ 004777 (Cat. No. 5567), SGC 0946 (Cat. No. 4541) and PD 0325901 (Cat. No. 4192).

Product Specifications for Crotonic Acid

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Crotonic Acid

The following data is based on the product molecular weight 86.09.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	11.62 mL	58.08 mL	116.16 mL
5 mM	2.32 mL	11.62 mL	23.23 mL
10 mM	1.16 mL	5.81 mL	11.62 mL
50 mM	0.23 mL	1.16 mL	2.32 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Fu Dynamics of telomere rejuvenation during chemical induction to pluripotent stem cells. Stem Cell Reports 2018 PMID: 29861168

Product Documents for Crotonic Acid