CTCE 9908

Name: CTCE 9908
Brand: Tocris Bioscience
SKU: 5130
Price: 295 USD
Availability: InStock

Tocris Bioscience | Catalog # 5130

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Citations (3)

Product Documents

CXCR4 antagonist; antitumor

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

CXCR4 antagonist; antitumor

View all Chemokine Receptor Antagonists »

Product Description

CTCE 9908 is a CXCR4 antagonist; induces mitotic catastrophe in ovarian cancer cells. Displays additive cytotoxic effects when given with taxol (Cat. No. 1097). Enhances the efficacy of docetaxel (Cat. No. 4056) in a mouse model.

Product Specifications for CTCE 9908

Molecular Weight

1927.27

Formula

C₈₆H₁₄₇N₂₇O₂₃

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

1030384-98-5

PubChem ID

90489012

InChI Key

VUYRSKROGTWHDC-ICWZLGNASA-N

SMILES

[H]N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCCCCC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N[H])CCCCN)C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Hassan CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or doce. in a transgenic mouse model. Int.J.Cancer. 2011 PMID: 20830712
Faber The many facets of SDF-1alpha, CXCR4 agonists and antagonists on hematopoietic progenitor cells. J.Biomed.Biotechnol. 2007 PMID: 17541466
Kwong An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells. Mol.Cancer Ther. 2009 PMID: 19567818

Product Documents for CTCE 9908

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for CTCE 9908

For research use only

Citations for CTCE 9908

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