CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.
CXCL2/GRO beta/MIP-2/CINC-3 Antibody (019) - Azide and BSA Free
Novus Biologicals | Catalog # NBP2-90391
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Mouse
Applications
ELISA, Sandwich ELISA Capture
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # 019 expressed in HEK293
Format
Azide and BSA Free
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Product Specifications
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CXCL2/GRO beta/MIP-2/CINC-3 (Uniprot#: P10889-1; Ala28-Asn100).
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Description
This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Applications for CXCL2/GRO beta/MIP-2/CINC-3 Antibody (019) - Azide and BSA Free
Application
Recommended Usage
ELISA
1:5000-1:10000
Sandwich ELISA Capture
1:250-1:2000
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
0.2 um filtered solution in PBS
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: CXCL2/GRO beta/MIP-2/CINC-3
Alternate Names
CINC-3, CINC3, GRO beta, MGSA-beta, MIP-2
Gene Symbol
CXCL2
Additional CXCL2/GRO beta/MIP-2/CINC-3 Products
Product Documents for CXCL2/GRO beta/MIP-2/CINC-3 Antibody (019) - Azide and BSA Free
Product Specific Notices for CXCL2/GRO beta/MIP-2/CINC-3 Antibody (019) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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- Troubleshooting Guide: ELISA
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
FAQs for CXCL2/GRO beta/MIP-2/CINC-3 Antibody (019) - Azide and BSA Free
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A: Mouse and rat do not have a gene which encodes CXCL8/IL-8. In mouse, the functional homologs to human CXCL8/IL-8 are CXCL1/KC and CXCL2/MIP-2. In rat, the functional homolog to CXCL8/human IL-8 is CXCL3/CINC-2.
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