CXCL3/GRO gamma, also known as DCIP-1 in mouse and CINC-2 in rat, is a member of the CXC chemokine family. Human CXCL3/GRO gamma is 107 amino acids (aa) in length, which includes a proposed signal peptide (aa 1–34), with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 65% and 59% aa sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl1 gene is homologous to human CXCL3/GRO gamma protein. CXCL3/GRO gamma is chemotactic for granulocytes, including neturophils.
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CXCL3/GRO gamma/CINC-2/DCIP-1 Antibody Pair [Biotin]
Novus Biologicals | Catalog # NBP3-57725
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Key Product Details
Assay Type
Sandwich ELISA
Sample Type
Cell culture supernatants from rabbits (Oryctolagus cuniculus). Can also be used to measure CXCL3 in a variety of biological sample types reported in the literature, including serum, plasma, whole blood, and tissue lysates from organs such as lung, spleen, liver, and bone marrow. While the kit is optimized for cell culture supernatants, minor modifications to the protocol may be required when in other sample types to ensure optimal sensitivity and accuracy, allowing researchers to adjust buffers, antibody concentrations, incubation times, temperatures, and other assay conditions as needed. (100 ul)
Reactivity
Rabbit
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Product Specifications
Description
The kit contains a capture antibody, detection antibody, and recombinant protein standard for assay development, and these antibodies have been validated to function together in an ELISA format using the provided standard. The quantities of kit components are not matched, and individual components may be purchased separately. This product is for research use only.
Sample Volume Required
100 ul
Conjugate
Biotin
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Storage of components varies. See protocol for specific instructions.
Background: CXCL3/GRO gamma/CINC-2/DCIP-1
Alternate Names
CINC-2, Dcip1, Gm1960, GRO gamma
Gene Symbol
Cxcl3
Additional CXCL3/GRO gamma/CINC-2/DCIP-1 Products
Product Documents for CXCL3/GRO gamma/CINC-2/DCIP-1 Antibody Pair [Biotin]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for CXCL3/GRO gamma/CINC-2/DCIP-1 Antibody Pair [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.
Related Research Areas
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FAQs for CXCL3/GRO gamma/CINC-2/DCIP-1 Antibody Pair [Biotin]
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Q: Are mouse or rat CXCL8/IL-8 products offered?
A: Mouse and rat do not have a gene which encodes CXCL8/IL-8. In mouse, the functional homologs to human CXCL8/IL-8 are CXCL1/KC and CXCL2/MIP-2. In rat, the functional homolog to CXCL8/human IL-8 is CXCL3/CINC-2.
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Associated Pathways
