CXCR1, also known as IL-8RA and CD181, is an approximately 60 kDa 7TM glycoprotein that functions as a receptor for the chemokine CXCL8/IL-8. It is expressed on neutrophils, monocytes, CD8 T cells, FoxP3+ CD4 Treg cells, mast cells, neuronal and glial cells, vascular endothelial cells, and melanoma. CXCR1 forms homodimers and heterodimers with CXCR2/IL-8RB. It can be cleaved from neutrophils in the lungs of cystic fibrosis patients to release fragments that promote CXCL8 production from airway epithelial cells. CXCR1 mediates neutrophil activation and chemotaxis to sites of inflammation as well as angiogenesis and melanoma invasiveness.
Rabbit CXCR1/IL-8RA - Ready-To-Use ELISA Kit (Colorimetric)
Novus Biologicals | Catalog # NBP3-54769
Key Product Details
Sample Type & Volume Required Per Well
Sensitivity
Assay Range
Product Specifications
Assay Type
Kit Type
Species
Description
Assay Length: 3 hours
精度
Intra-Assay Precision (Precision within an assay) %CV 10 (example only; lot dependent)
Inter-Assay Precision (Precision between assays) %CV 12 (example only; lot dependent)
Kit Contents for Rabbit CXCR1/IL-8RA - Ready-To-Use ELISA Kit (Colorimetric)
- Pre-coated 96T strip plate, Plate sealer for 96 wells, Standard, Standard Diluent, Detection Solution A, Detection Solution B, TMB Substrate, Stop Solution, Wash Buffer (30 x concentrate), Instruction manual
Preparation and Storage
Stability & Storage
Background: CXCR1/IL-8RA
Long Name
Alternate Names
Gene Symbol
Additional CXCR1/IL-8RA Products
Product Documents for Rabbit CXCR1/IL-8RA - Ready-To-Use ELISA Kit (Colorimetric)
Certificate of Analysis
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Product Specific Notices for Rabbit CXCR1/IL-8RA - Ready-To-Use ELISA Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
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