20 results for "Cell Adhesion Inhibitors" in 产品
Cell Adhesion Inhibitors
Cellular adhesion molecules (CAMs) are a large family of transmembrane proteins that link the cytoskeleton and intracellular signaling cascades with the extracellular environment. Cell adhesion molecules have roles in cell proliferation, differentiation, motility, trafficking, apoptosis and tissue architecture, and their dysregulation is common in cancer.
There are four major families of cell adhesion molecules:
- Immunoglobulin Superfamily (IgSF) CAMs - bind to integrins and members of this ...
Anticoagulant
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
| Purity: | ≥95% |
Selective inhibitor of P-selectin-mediated cell adhesion
| Chemical Name: | 3-[7-(2,4-Dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-2H-pyran-2-one |
| Purity: | ≥97% |
Glycoprotein IIb/IIIa (integrin αIIbβ3) receptor antagonist. Antithrombotic
| Chemical Name: | 4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride |
| Purity: | ≥98% |
Integrin binding sequence; inhibits integrin receptor function
| Purity: | ≥95% |
Antiangiogenic. Heparanase inhibitor
| Chemical Name: | 2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid |
| Purity: | ≥97% |
Selective α4β1 (VLA-4) inhibitor
| Purity: | ≥95% |
Fluorescent ligand for α4β1 (VLA-4)
| Purity: | ≥90% |
Potent and selective α1β1 inhibitor
| Purity: | ≥95% |
Sialic acid analog; sialyltransferase inhibitor
| Chemical Name: | 5-(Acetylamino)-3,5-dideoxy-3-fluoro-D-erythro-α-L-manno-2-nonulopyranosonic acid methyl ester 2,4,7,8,9-pentaacetate |
| Purity: | ≥97% |
Selective inhibitor of E-selectin and ICAM-1 expression
| Chemical Name: | 4-[(4-Methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide |
| Purity: | ≥98% |
Potent α2β1 inhibitor; displays antithrombotic activity in vivo
| Chemical Name: | N-[[(4R)-5,5-Dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-L-alanine |
| Purity: | ≥98% |
αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor
| Purity: | ≥95% |
α4β1 (VLA-4) antagonist
| Chemical Name: | 1-[[(3S)-4-[2-[4-[[[(2-Methylphenyl)amino]carbonyl]amino]phenyl]acety]l-3-morpholinyl]carbonyl]-4-piperidinediacetic acid |
| Purity: | ≥98% |
Potent inhibitor of the LFA-1/ICAM-1 interaction
| Chemical Name: | (2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one |
| Purity: | ≥98% |
Potent inhibitor of the LFA-1/ICAM interaction
| Chemical Name: | 6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4,4]non-7-yl]-3-pyridinecarboxylic acid |
| Purity: | ≥98% |
Heparin sulfate antagonist
| Chemical Name: | N,N'-Bis(4-amino-2-methyl-6-quinolinyl)urea dihydrochloride |
| Purity: | ≥98% |
Disrupts MTDH and SND1 interaction, enhances immune surveillance
| Chemical Name: | 5-Chloro-2-methoxy-N-(2-methyl[1,2,4]triazolo[1,5-a]pyridin-8-yl)benzenesulfonamide |
| Purity: | ≥98% |
ctRAGE-DIAPH1 interaction antagonist; reduces inflammatory signaling in diabetic mice
| Chemical Name: | N-[4-[7-Cyano-4-(4-morpholinylmethyl)-2-quinolinyl]phenyl]acetamide |
| Purity: | ≥98% |
Potent integrin inhibitor (αvβ3/αvβ6); also improves stem cell attachment in 3D cell culture scaffolds
| Purity: | ≥95% |
