The name of Aminopetidase PILS (Puromycin-insensitive Leucyl-specific) describes the two basic properties of this zinc metalloproteinase in vitro. Also known as ALAP (Adipocyte-derived Leucine Aminopeptidase), Aminopeptidase regulator of TNFR1 shedding 1 (ARTS1), and ER Aminopeptidase ERAP1 or ERAAP, it is encoded by the ARTS1 gene. Aminopeptidase PILS is thought to regulate antigen presentation, promote TNFR1 and IL-6 R ectodomain shedding, and may be associated with hypertension.
Cynomolgus Monkey ARTS1 (XP_005557484) VersaClone cDNA
R&D Systems | Catalog # RDC2909
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Background: Aminopeptidase PILS/ARTS1
Long Name
Aminopeptidase Puromycin-insensitive Leucyl-specific
Alternate Names
A-LAP, ARTS1, ERAAP1, ERAP1, PILS-AP
Gene Symbol
ERAP1
UniProt
Additional Aminopeptidase PILS/ARTS1 Products
Product Documents for Cynomolgus Monkey ARTS1 (XP_005557484) VersaClone cDNA
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Product Specific Notices for Cynomolgus Monkey ARTS1 (XP_005557484) VersaClone cDNA
For research use only
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