Desloratadine

Tocris Bioscience | Catalog # 5958

High affinity H1 antagonist; anti-inflammatory
Tocris Bioscience
Discontinued Product
5958 has been discontinued. View all Histamine H1 Receptor Antagonists products.

Key Product Details

Description

High affinity H1 antagonist; anti-inflammatory

Product Description

Desloratadine is a high affinity histamine H1 receptor antagonist (Ki = 0.87 nM); active metabolite of loratadine (Cat. No. 1944). Anti-inflammatory.

Product Specifications for Desloratadine

Molecular Weight

310.82

Formula

C19H19ClN2

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

CAS Number

100643-71-8

PubChem ID

124087

InChI Key

JAUOIFJMECXRGI-UHFFFAOYSA-N

SMILES

ClC1=CC=C2C(CCC3=C(/C2=C4CCNCC\4)N=CC=C3)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 6.22 20
Ethanol 31.08 100

Preparing Stock Solutions for Desloratadine

The following data is based on the product molecular weight 310.82.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.22 mL 16.09 mL 32.17 mL
5 mM 0.64 mL 3.22 mL 6.43 mL
10 mM 0.32 mL 1.61 mL 3.22 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Desloratadine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Desloratadine

For research use only

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